SUPPORTING RESOURCES

Peer-developed
educational materials

Here you will find a broad range of educational resources to support your HER2 IHC scoring consistency and best practice recommendations from the Pathology Faculty. View the materials, including The significance of HER2 documentary, below.

Consistency with practice: Standardizing the approach to HER2 IHC scoring

Dr. Hicks discusses the importance of pre-analytic, analytic, and post-analytic variables. Dr. Khoury and Dr. Tozbikian review artifacts and indeterminate staining patterns. (57 mins)

Challenge accepted: Best practices for scoring HER2 across the spectrum

Dr. Jaffer provides guidance on recognition of HER2 staining patterns and heterogeneity. Dr. Krishnamurthy and Dr. Bui present challenging HER2 IHC cases. (60 mins)

The significance of HER2: Trailer

A short preview of a mini documentary-style film presented by Dr. Marilyn Bui and Dr. Hope S. Rugo. (2 mins)

The significance of HER2

Dr. Marilyn Bui, pathologist, and Dr. Hope S. Rugo, oncologist, discuss the evolution of HER2 as a breast cancer biomarker in this mini documentary-style film. (19 mins)

Lives behind slides

This short animation depicts patients with breast cancer, whose lives are impacted by their HER2 status. (2 mins)

CAP, College of American Pathologists; HER2, human epidermal growth factor receptor 2; IHC, immunohistochemistry; USCAP, United States and Canadian Academy of Pathology.

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Microscopy review: Slide validation

Dr. Bui discusses specimen requirements and recommendations to reduce pre-analytical variables. (17 mins) 

Microscopy review: Approaching the scoring

Dr. Tozbikian demonstrates current approaches to HER2 IHC scoring. (17 mins)

Microscopy review: Areas of diagnostic pitfalls

Dr. Hicks highlights considerations when interpreting HER2 status. (19 mins)

Recognizing HER2 staining patterns at the low end of the spectrum

A short animation, discussing best practice recommendations for scoring HER2 by IHC with Dr. Feldman. (4 mins)

Topic 1: Clinical innovation across the HER2 pathway

Dr. Krishnamurthy presents the evolution of HER2 in clinical practice. (7 mins)

Topic 2: The spectrum of HER2 expression

Dr. Tozbikian reviews current HER2 guidelines and the significance of discrete HER2 IHC scoring. (9 mins)

Topic 3: Overcoming challenges in assessing HER2 expression across the spectrum

Dr. Hicks highlights best clinical practices for differentiating low levels of HER2. (11 mins)

Pathology in practice: The breast HER2 spectrum

A webinar hosted by the CAP Foundation highlighting the evolution of practice guidelines for HER2 testing in breast cancer. (50 mins)

Microscopy review: Slide validation

Dr. Bui discusses specimen requirements and recommendations to reduce pre-analytical variables. (17 mins) 

From past to present: The significance of HER2 in breast cancer

Dr. Jaffer provides guidance on recognition of HER2 staining patterns and heterogeneity. Dr. Krishnamurthy and Dr. Bui present challenging HER2 IHC cases. (60 mins)

Microscopy review: Correlating interpretation with clinical history 

Dr. Feldman discusses histopathologic findings in view of the clinical background. (15 mins)